| EPSRC Reference: |
GR/K56421/01 |
| Title: |
SYNTHESIS OF BRYOSTATINS: APPLICATIONS OF REMOTE ASYMMETRIC INDUCTION TO ORGANIC SYNTHESIS |
| Principal Investigator: |
Thomas, Professor EJ |
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| Department: |
Chemistry |
| Organisation: |
Victoria University of Manchester, The |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 January 1996 |
Ends: |
28 February 1999 |
Value (£): |
142,063
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Summary on Grant Application Form |
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Bryostatins are important natural products in phase 2 clinical trials for the treatment of cancers including lymphomas, melanomas, ovarian and renal cancers. It is proposed to synthesize these compounds using novel methodology based on our recently discovered procedures for remote asymmetric induction. This will test our chemical methodology in a complex system and make analygues of the bryostatins available for biological evaluation.
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Key Findings |
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Potential use in non-academic contexts |
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Impacts |
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| Description |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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