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Details of Grant 

EPSRC Reference: GR/J73704/01
Title: SEQUENCE DEPENDENT DNA STRUCTURE
Principal Investigator: Hunter, Professor CA
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Chemistry
Organisation: University of Sheffield
Scheme: Standard Research (Pre-FEC)
Starts: 24 November 1994 Ends: 23 November 1997 Value (£): 17,066
EPSRC Research Topic Classifications:
Biological & Medicinal Chem.
EPSRC Industrial Sector Classifications:
Related Grants:
Panel History:  
Summary on Grant Application Form
(1) Calculate the - interactions in single base-pair steps for all possible combinations base-pairs in all possible conformations.(2) Calculate the conformational restrictions imposed by the backbone.(3) Determine low energy conformations for longer DNA sequences.(4) Use these calculations to investigate the molecular basis of sequence-specific DNA recognition by proteins and drugs.
Key Findings
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Summary
Date Materialised
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Organisation Website: http://www.shef.ac.uk