| EPSRC Reference: |
GR/J63019/01 |
| Title: |
NEW METHODS FOR THE SYNTHESIS OF BIOACTIVE POLYPROPIONATES: APPLICATIONS TO DISCODERMOLIDE AND SIPHONARIN B |
| Principal Investigator: |
Paterson, Professor I |
| Other Investigators: |
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| Department: |
Chemistry |
| Organisation: |
University of Cambridge |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
13 August 1994 |
Ends: |
12 August 1996 |
Value (£): |
90,056
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| EPSRC Research Topic Classifications: |
| Biological & Medicinal Chem. |
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Summary on Grant Application Form |
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(1) Total synthesis of the immunosuppresant lactone discodermolide;(2) Total synthesis of siphonarin B and the study of silica gel-mediated cyclisation modes of its open-chain precursors;(3)The development of practical methods for acyclic stereocontrol using the aldol chemistry of lactate-derived ketones.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.cam.ac.uk |