| EPSRC Reference: |
GR/S68880/01 |
| Title: |
Basic Technology : 4 Billion Bases a Day - Practical Individual Genome Sequencing |
| Principal Investigator: |
Bland, Professor JAC |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Physics |
| Organisation: |
University of Cambridge |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 September 2003 |
Ends: |
29 February 2008 |
Value (£): |
2,348,816
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| EPSRC Research Topic Classifications: |
| Analytical Science |
Biological & Medicinal Chem. |
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| EPSRC Industrial Sector Classifications: |
| Pharmaceuticals and Biotechnology |
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| Related Grants: |
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| Panel History: |
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Summary on Grant Application Form |
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The proposal described below is fundamentally a new method of synthesising, screening and sequencing DNA at a rate that is thousands of times faster than existing methods. If successful it will allow over 4 billion bases to be sequenced in less than a day on one instrument! The magnitude of what is being proposed here is quite literally mind-boggling and will cause a revolution in all areas of human health forever changing the landscape of biological and medicinal sciences. En route spin off applications will include the rapid and comprehensive identification of all single base changes within a given person's genome, the ability to analyse large numbers of people for the presence of single changes at an unprecedented rate, a method for rapidly and cheaply producing huge numbers (100,000s) of defined oligonucleotide sequences, and the use of this methodology to change current DNA array technology as well as the ultimate aim of sequencing billions of bases a day.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.cam.ac.uk |