| EPSRC Reference: |
GR/R83484/01 |
| Title: |
Computer simulation of protein denaturation, aggregation and gelation |
| Principal Investigator: |
Euston, Professor S |
| Other Investigators: |
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| Department: |
Sch of Life Sciences |
| Organisation: |
Heriot-Watt University |
| Scheme: |
Fast Stream |
| Starts: |
06 January 2003 |
Ends: |
05 January 2006 |
Value (£): |
62,468
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| EPSRC Research Topic Classifications: |
| Complex fluids & soft solids |
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Summary on Grant Application Form |
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Current computer simulation models of aggregation and gelation assume that the constituent particles are spherical. Whereas this may be a good approximation in many circumstances for some protein gels this may be an oversimplification. Globular proteins denature and gel on heating. Denaturation is characterised by large structural changes in the molecule. This aspect of protein gelation is not accounted for in models that treat particles as spheres. A model for protein gelation will be developed that treats proteins as globular molecules that unfold (denature) and aggregate when heated. An improved understanding of the mechanisms of protein gelation will benefit both food manufacturers and experimental researchers in the field of protein gelation.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.hw.ac.uk |