| EPSRC Reference: |
GR/R80421/01 |
| Title: |
Synthesis and Study of Chiral Cyclophanes |
| Principal Investigator: |
Gibson, Professor SE |
| Other Investigators: |
|
| Researcher Co-Investigators: |
|
| Project Partners: |
|
| Department: |
Chemistry |
| Organisation: |
Kings College London |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 October 2002 |
Ends: |
31 December 2003 |
Value (£): |
97,216
|
| EPSRC Research Topic Classifications: |
|
| EPSRC Industrial Sector Classifications: |
| Chemicals |
Pharmaceuticals and Biotechnology |
|
| Related Grants: |
|
| Panel History: |
|
|
Summary on Grant Application Form |
|
Ever since Cram's pioneering work on cyclophanes, there has been considerable interest in these molecules. Much of the earlier work focussed on smaller members of the class, but more recently, attention has turned to using cyclophanes of all sizes to study the effects of bringing different functional groups into close proximity. Cyclophanes are starting to be used in several areas of contemporary chemistry; in particular their stereochemical properties are fascinating, but not yet fully understood.A serendipitous synthesis of a [13,13] paracyclophane has prompted us to devise a new route to chiral cyclophanes. We wish to execute this synthesis, test its versatility and look at the co-ordination chemistry of the diverse structures thus generated. It is anticipated that some of the metal complexes synthesised will have catalytic properties and applications in asymmetric synthesis.
|
|
Key Findings |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Potential use in non-academic contexts |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Impacts |
|
| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
|
| Date Materialised |
|
|
|
|
Sectors submitted by the Researcher |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
| Project URL: |
|
| Further Information: |
|
| Organisation Website: |
|