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Details of Grant 

EPSRC Reference: GR/R52251/01
Title: Computer Assisted Surgery in Total Knee Replacement - A Feasibility Study
Principal Investigator: Seedhom, Dr BB
Other Investigators:
Researcher Co-Investigators:
Mr S Porada
Project Partners:
Leeds Teaching Hospitals NHS Trust University of Leeds
Department: School of Medicine
Organisation: University of Leeds
Scheme: Standard Research (Pre-FEC)
Starts: 01 December 2001 Ends: 30 November 2002 Value (£): 62,471
EPSRC Research Topic Classifications:
Biomaterials Robotics & Autonomy
EPSRC Industrial Sector Classifications:
Healthcare
Related Grants:
Panel History:  
Summary on Grant Application Form
Four contra-lateral pairs of cadaveric knees will be used in this study. Using one of the joints in a pair, 2-D images of knee joint specimen anatomy are acquired using computer-aided tomography (CAT) from which 3-D versions are constructed. Computerised models of joint bones are aligned into the natural configurations in collaboration with a surgeon. The alignment process might result in intersections of volumes thus identifying sites and volumes of minimum bone removal necessary just to achieve correction of bone positions. Computerised models of typical TKR implant designs in current use are superimposed and re-oriented for best fit (and least bone removal). Personalised guides and tools will then be designed using a CAD software package. These are intended to help effecting the planned bone removal, and their design will first be validated on the computer model; (a) to ensure their accurate positioning on the joint surfaces during surgery and (b) to guide the cutting blades used in bone removal and thus result in accurate implant fitting. The tools are then manufactured using rapid prototyping technology and their efficacy is validated on the cadaveric specimens, to install the implants. Further validation is undertaken when new (post-operative) images of the specimens are generated, and results are compared to the preoperative images, and also to outcome with knees from the contralateral side in each pair, on which the procedure of implantation is performed in the conventional manner.
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Further Information:  
Organisation Website: http://www.leeds.ac.uk