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Details of Grant 

EPSRC Reference: GR/R42733/01
Title: Dissolution Kinetics of Lecithin/Bile Salt/Cholesterol Mixtures
Principal Investigator: Egelhaaf, Professor S
Other Investigators:
Researcher Co-Investigators:
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Department: Sch of Physics and Astronomy
Organisation: University of Edinburgh
Scheme: ROPA
Starts: 01 April 2001 Ends: 31 March 2003 Value (£): 101,002
EPSRC Research Topic Classifications:
Complex fluids & soft solids
EPSRC Industrial Sector Classifications:
No relevance to Underpinning Sectors
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Panel History:  
Summary on Grant Application Form
We propose to examine, mainly by experiment, the swelling and dissolution behaviour of lecithin/bile salt/cholesterol mixtures. This is made possible by combining two strands of recent work (dissolution of amphiphiles and bilayer formation kinetics in lecithin/bile salt mixtures). As well as illuminating the generic physics of phase transition kinetics using a tunable model system, this should also shed light on the physical processes involved in lipid solubilazation in the digestive tract. Indeed, we plan to explore analogies between digestion and detergency - how similar is the stomach to a washing machine?
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Organisation Website: http://www.ed.ac.uk