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Details of Grant 

EPSRC Reference: GR/R24418/01
Title: Novel Measurements of Nonlinear Interactions In Evoked Acoustic Emissions of the Inner Ear
Principal Investigator: Kapadia, Dr S
Other Investigators:
Lutman, Professor ME
Researcher Co-Investigators:
Project Partners:
Department: Inst of Sound and Vibration Research
Organisation: University of Southampton
Scheme: Fast Stream
Starts: 04 September 2001 Ends: 03 March 2003 Value (£): 59,221
EPSRC Research Topic Classifications:
Digital Signal Processing Med.Instrument.Device& Equip.
EPSRC Industrial Sector Classifications:
Healthcare
Related Grants:
Panel History:  
Summary on Grant Application Form
Otoacoustic emissions (OAEs) are low-level acoustic responses that are emitted by the normal human inner ear (cochlea) in response to external stimuli such as clicks and tone bursts. OAEs are of great clinical value, particularly in newborn hearing screening - millions of newborns worldwide are tested using OAEs every year, and the Department of Health is about to launch a screening initiative in the UK. OAEs are also gaining increasing importance as a research tool in studying the human cochlea. However, their generation mechanisms and hence how they can best be measured remain poorly understood. In particular, click-evoked OAEs measured using the maximum length sequence (MLS) technique exhibit a type of nonlinear behaviour, whose origin is unexplained. The investigators have previously proposed a model which appears broadly to account for the observed nonlinear behaviour, subject to certain assumptions. The primary assumption is that individual frequency components within a broad-band click-evoked OAE are generated in a nonlinear fashion, but sum linearly with each other. The assumption could be tested if the MLS technique were developed to measure OAEs evoked by tone bursts, as well as the clicks that have been used previously. The present proposal seeks to develop a system to conduct such measurements, to obtain this new class of data and to test and develop the above model of OAE nonlinearity. The project would extend the investigators' own research, but also facilitate new lines of research into OAEs and enhance their possibilities in clinical applications.
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Organisation Website: http://www.soton.ac.uk