| EPSRC Reference: |
GR/N16747/01 |
| Title: |
ANATOMICAL FLOW MODELS FOR CALIBRATION BLOOD VELOCITY MEASUREMENTS MADE USING DOPPLER ULTRASOUND |
| Principal Investigator: |
Hoskins, Professor PR |
| Other Investigators: |
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| Project Partners: |
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| Department: |
Medical and Radiological Sciences |
| Organisation: |
University of Edinburgh |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 October 2000 |
Ends: |
31 July 2004 |
Value (£): |
427,389
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| EPSRC Research Topic Classifications: |
| Development (Biosciences) |
Instrumentation Eng. & Dev. |
| Intelligent Measurement Sys. |
Multiphase Flow |
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| EPSRC Industrial Sector Classifications: |
| Healthcare |
No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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Improved diagnosis of arterial disease relies on the development of non-invasive methods to measure blood velocity and related quantities (eg wall shear rate and volumetric flow) and these methods must be accurate in the complex 3D flows occurring in-vivo. Accuracy cannot be assessed in-vivo, and the flow field in straight tube models is not representative of that in real vessels. This project develops anatomical flow models with known velocity fields suitable for assessment of velocity accuracy measured using Doppler ultrasound. An acoustically equivalent polyurethane suitable for making the vessel wall will be developed. Mould manufacture will use rapid prototyping techniques based on 3D MRI datasets from human arteries. The vessel wall movement of the models is measured optically and adjusted to match that of human arteries. Acoustically equivalent models and identical optically transparent models are built. Knowledge concerning the 3D time varying flow field is obtained using the optical models; velocity is measured using an optical tracking technique. The models are used to investigate the accuracy of maximum velocity and volumetric flow measured using commercial Doppler systems, maximum velocity measured using a prototype real time dual beam Doppler system, and wall shear rate measured using a prototype colour flow technique.EngProg\
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.ed.ac.uk |