| EPSRC Reference: |
GR/N05635/01 |
| Title: |
COMBINED SOLID-STATE NMR & POWDER DIFFRACTION CRYSTAL STRUCTURE DETERMINATION |
| Principal Investigator: |
Harris, Professor RK |
| Other Investigators: |
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| Project Partners: |
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| Department: |
Chemistry |
| Organisation: |
Durham, University of |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 September 2000 |
Ends: |
31 August 2003 |
Value (£): |
169,460
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| EPSRC Research Topic Classifications: |
| Catalysis & Applied Catalysis |
Chemical Structure |
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| EPSRC Industrial Sector Classifications: |
| Manufacturing |
Chemicals |
| Pharmaceuticals and Biotechnology |
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Summary on Grant Application Form |
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Funding is requested t support a thirty month research programme to allow the development of a methodology that combines the experimental techniques of solid-state NMR and powder x-ray diffraction to solve the crystal structures of complex speciality fine chemicals from powdered samples. The research seeks to provide general protocols that exploit the individual techniques optimally for their use, in combination, to solve crystal structures, and to provide computational methods for data processing and crystal structure refinement. The research will focus on crystalline materials that have more than one moiety in their asymmetric units including, for example, solvates and molecular complexes. In such cases it is necessary to exploit a combination of experimental data from the two techniques to sufficiently constrain a problem to enable successful structure solution. Materials that manifest polymorphism will be studied in particular so as to begin to address the underlying structural causes. In addition the research will address the issue of the characterisation of solid to solid polymorphic transformations.EngProg\
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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