| EPSRC Reference: |
GR/N04324/01 |
| Title: |
NETWORK: ENGINEERING VIRTUAL TISSUES AND ORGANS |
| Principal Investigator: |
Holden, Professor A |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
School of Biomedical Sciences |
| Organisation: |
University of Leeds |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 April 2000 |
Ends: |
30 September 2002 |
Value (£): |
51,943
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| EPSRC Research Topic Classifications: |
| Development (Biosciences) |
Image & Vision Computing |
| Modelling & simul. of IT sys. |
Theoretical biology |
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| EPSRC Industrial Sector Classifications: |
| Healthcare |
No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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Information about biological structure and function is so detailed and complicated that any attempt at understanding integrative functions of tissues and organs must be computational. Visualisation of such detailed computational models form virtual tissues. These can be used as research tools, for the virtual screening of pharmaceutical agents, the evaluation of electrical interventions (pacemakers, defibrillators, low frequency EMF effects) and as the knowledge bases for interpreting clinical signals. To date, most progress has been made in the virtual engineering of the heart, but construction of virtual cardiac tissues has been made in the virtual engineering of the heart, but construction of virtual cardiac tissues has been fragmentary, using different data representations and model structures.This network will provide the UK with the opportunity to develop a common computational and visualisation framework within which different groups can work and collaborate in constructing virtual tissue models, from components produced at different sites. Although primarily focussed on the electrical and mechanical activity of excitable, locally interacting tissues, many of the problems, and hence tool specifications, can be generalised to other tissue and organ systems.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.leeds.ac.uk |