| EPSRC Reference: |
GR/M51000/01 |
| Title: |
DEVELOPMENT OF TWO-PHOTON CONFOCAL AND TIME-RESOLVED IMAGING MICROSCOPY |
| Principal Investigator: |
Phillips, Professor D |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Chemistry |
| Organisation: |
Imperial College London |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 August 1999 |
Ends: |
31 October 2002 |
Value (£): |
404,830
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| EPSRC Research Topic Classifications: |
| Biological & Medicinal Chem. |
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| EPSRC Industrial Sector Classifications: |
| Healthcare |
Pharmaceuticals and Biotechnology |
| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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It is proposed to rebuild and improve the temporal and spatical resolution of a fluorescence lifetime imaging microscope (FLIM) based upon single-photon counting detection. The new instrument will permit two-photon excitation of fluorescence, enhancing greatly the confocal and spatial performance. The use of short pulse excitation will further enhance time resolution, permitting study of the details of photochemical kinetics of sensitisers and molecular probes inside living cells.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.imperial.ac.uk |