| EPSRC Reference: |
GR/M50584/01 |
| Title: |
SYNTHETIC DEVELOPMENT OF AN INTRAMOLECULAR BAYLIS-HILLMAN REACTION |
| Principal Investigator: |
Murphy, Dr P |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Sch of Chemistry |
| Organisation: |
Bangor University |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 October 1999 |
Ends: |
30 September 2002 |
Value (£): |
48,630
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| EPSRC Research Topic Classifications: |
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| EPSRC Industrial Sector Classifications: |
| Pharmaceuticals and Biotechnology |
No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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The aim of this project is to investigate a recently discovered method for effecting an intramolecular variant of the Baylis-Hillman reaction. As part of this project we will investigate the reaction to discover methods for the improvement of yield and reaction rate and the general effects of catalyst and conditions and thus gain insight in the mechanism and scope of the process. Efforts will be made to develop an asymmetric version of the reaction and the effects of both internal and external stereocontrol of the reaction will be investigated. Applications of this reaction in the synthesis of carbocyclic and heterocyclic molecules will be investigated, together with approaches to the synthesis of natural products.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.bangor.ac.uk |