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Details of Grant 

EPSRC Reference: GR/M44187/01
Title: BROADLY TUNABLE OPOS FOR MULTIPHOTON MICROSCOPY
Principal Investigator: Ferguson, Professor AI
Other Investigators:
Langford, Dr N
Researcher Co-Investigators:
Project Partners:
Pre Nexus Migration
Department: Physics
Organisation: University of Strathclyde
Scheme: Standard Research (Pre-FEC)
Starts: 01 April 1999 Ends: 31 December 2001 Value (£): 196,180
EPSRC Research Topic Classifications:
Lasers & Optics
EPSRC Industrial Sector Classifications:
Manufacturing
Related Grants:
Panel History:  
Summary on Grant Application Form
Multiphoton microscopy is in the process of revolutionising imaging in the biological sciences and is likely to have an effect in non-destructive testing and analysis in the physical sciences. In multiphoton imaging, depth sectioning is made possible by use of multiphoton absorption in fluorescent materials. In order for the process to be efficient a source of femtosecond pulses is required with a repetition rate comparable to the inverse of the fluorescence lifetime of the fluorophore. Although the technique works extremely well at selected wavelengths there is a strong desire for a broadly tunable source which can be optimised for the system being investigated. In many systems the excitation and fluorescence wavelength gives important information on the detail of processes within the sample. There are very tight constraints on the efficiency, compactness and reliability of the excitation source which makes an all solid state synchronously pumped optical parametric oscillator (OPO) an excellent solution. This project will be primarily concerned with demonstrating the feasibility of a sub-picosecond OPO based on periodically poled KTP for this purpose. This source will be incorporated into an existing scan head which will provide a unique capability.
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Organisation Website: http://www.strath.ac.uk