| EPSRC Reference: |
GR/M43067/01 |
| Title: |
APPROACHES TO THE DEVELOPMENT OF A PROSTHETIC CORNEA |
| Principal Investigator: |
Hodson, Professor S |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Optometry and Vision Sciences |
| Organisation: |
Cardiff University |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 March 1999 |
Ends: |
30 November 2002 |
Value (£): |
160,522
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| EPSRC Research Topic Classifications: |
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| EPSRC Industrial Sector Classifications: |
| Healthcare |
No relevance to Underpinning Sectors |
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| Panel History: |
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Summary on Grant Application Form |
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The transparency of the cornea is not understood but is, in a subtle way, a function of the repulsive ordering forces between neighbouring fibrils (which are in diameter about 1/20th of the wavelength of yellow light). On its own, each fibril scatters significant quantities of incident light sufficient to render the cornea opaque but there is a co-operative interference phenomenon between neighbouring fibrils which render the cornea transparent. Current theories on this co-operative phenomenon have recently been shown to be wrong. We have discovered a novel way of reversibly modulating the repulsive force between the fibre fibrils which would allow an explicit relationship between transparency and fibrillar order (which is somewhere in between a lattice like order and a liquid-like order) sufficient to define the requirements for transparency and to allow prosthetic models.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.cf.ac.uk |