| EPSRC Reference: |
GR/M39060/01 |
| Title: |
ROPA: THE DEVELOPMENT AND APPLICATION OF SPATIO- TEMPORAL MATHEMATICAL MODELS OF VASCULAR TUMOUR GROWTH |
| Principal Investigator: |
Lewis, Professor C |
| Other Investigators: |
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| Project Partners: |
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| Department: |
Oncology & Pathology |
| Organisation: |
University of Sheffield |
| Scheme: |
ROPA |
| Starts: |
01 June 1999 |
Ends: |
31 May 2001 |
Value (£): |
76,784
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| EPSRC Research Topic Classifications: |
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| EPSRC Industrial Sector Classifications: |
| Pharmaceuticals and Biotechnology |
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Summary on Grant Application Form |
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The main aim of this project is to develop mathematical models that describe the spatio-temporal heterogeneity that characterises vascular tumour growth. The proposal encompasses several active areas of mathematical research, such as mathematical modelling, spatio-temporal dynamics and numerical methods for solving mixed systems of equations. The principle challenge will be developing realistic models of vascular tumour growth. A crucial aspect of this will be successfully incorporating, at a macroscopic level, microscopic effects involving the vascular morphology. The models will provide a mathematical framework for predicting and comparing the effects and efficacy of anti-angiogenic therapeutic agents such as endostatin and angiostatin.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.shef.ac.uk |