| EPSRC Reference: |
GR/M33532/01 |
| Title: |
ASYMMETRIC PROTONATION OF ORGANOMETALLICS |
| Principal Investigator: |
Simpkins, Professor NS |
| Other Investigators: |
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| Department: |
Sch of Chemistry |
| Organisation: |
University of Nottingham |
| Scheme: |
ROPA |
| Starts: |
04 January 1999 |
Ends: |
03 July 2000 |
Value (£): |
72,256
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| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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Although stereoselective protonation of enolates has been widely examined, the corresponding area of chemistry involving protonation of organometallics remains unexplored. The proposed research aims to establish the viability of this novel type of asymmetric synthesis, which could provide useful access to enantiomerically enriched chiral products. Racemic organometallics, especially configurationally unstable benzylic types, will be screened with a range of appropriate chiral protonating agents in order to establish conditions for highly enantioselective protonation. The scope for efficient generation of chiral materials of various types will be explored, as well as possibilities for catalytic variants.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.nottingham.ac.uk |