| EPSRC Reference: |
GR/M00978/02 |
| Title: |
ISONITRILE LIGANDS IN ASYMMETRIC CATALYSIS |
| Principal Investigator: |
Gibson, Professor SE |
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| Department: |
Chemistry |
| Organisation: |
Kings College London |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 January 1999 |
Ends: |
30 September 2001 |
Value (£): |
50,532
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| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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We have recently discovered a method for converting metal-carbonyl ligands M-CO into metal-isonitrile ligands M-CNR which circumvents the use of malodorous and toxic isonitriles themselves. The method readily generates non-racemic chiral isonitrile ligands, a class of ligand which has been overlooked in asymmetric catalysis to date.We propose to analyse the properties of non-racemic chiral isonitrile ligands and their potential in asymmetric catalysis by synthesising complexes which are predicted to have Lewis acid activity and then examining the effectiveness of the asymmetric environment created by the isonitrile ligands using assays based on three synthetically important reactions.
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Key Findings |
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Potential use in non-academic contexts |
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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