EPSRC Reference: |
GR/L82755/01 |
Title: |
THE EFFECT OF CSF ON CEREBRAL IMAGE RECONSTRUCTION USING OPTICAL TOMOGRAPHY |
Principal Investigator: |
Delpy, Professor DT |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
Medical Physics and Biomedical Eng |
Organisation: |
UCL |
Scheme: |
Standard Research (Pre-FEC) |
Starts: |
01 August 1998 |
Ends: |
31 July 2001 |
Value (£): |
158,471
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EPSRC Research Topic Classifications: |
Instrumentation Eng. & Dev. |
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EPSRC Industrial Sector Classifications: |
No relevance to Underpinning Sectors |
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Related Grants: |
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Panel History: |
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Summary on Grant Application Form |
The project is centred around the development of a methodology for reconstructing images from near-infrared spectroscopy data for the diagnosis of hypoxic ischaemic injury in newborn infacts. One requirement of such an imaging technique is a fast and accurate model of light propagation in tissue. Current models are limited to two dimensions, due to memory limitations and are only valid in scattering regions due to assumptions made in the model.Previous experimental and theoretical work carried out at UCL has shown that the presence of the non scattering CFS layer around the brain is likely to have a significant effect on the propagation of NIR light through the head. The work proposed in this application will investigate the effect of this CSF layer on the problem of NIR image reconstruction and attempt to improve the modelling of light transport in inhomogeneous objects with non scattering regions in order to include this effect in image reconstructions of the neonatal head. The project will also investigate the potential of reducing the memory requirements of the current model by using logarithmic interpolation in the elements of the finite element model of light transport, which would allow the possibility of more accurate 3D modelling.
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Key Findings |
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Potential use in non-academic contexts |
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Impacts |
Description |
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Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
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Project URL: |
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Further Information: |
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Organisation Website: |
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