| EPSRC Reference: |
GR/L80331/01 |
| Title: |
THE AZIDE APPROACH TO VINDOLINE AND CARBOXYVELBANAMINE COMPONENT ALKALOIDS OF VINBLASTINE |
| Principal Investigator: |
Murphy, Professor JA |
| Other Investigators: |
|
| Researcher Co-Investigators: |
|
| Project Partners: |
|
| Department: |
Pure and Applied Chemistry |
| Organisation: |
University of Strathclyde |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
02 July 1998 |
Ends: |
01 July 2001 |
Value (£): |
170,828
|
| EPSRC Research Topic Classifications: |
|
| EPSRC Industrial Sector Classifications: |
| No relevance to Underpinning Sectors |
|
|
| Related Grants: |
|
| Panel History: |
|
|
Summary on Grant Application Form |
|
The highly effective anti-tumour agents vinblastine and vincristine are pseudo-dimeric alkaloids comprising a vindoline and a carboxyvelbanamine unit. This proposal suggests a new stereoselective route to these two component alkaloids by exploiting recently discovered free radical chemistry of the azide group.
|
|
Key Findings |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Potential use in non-academic contexts |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Impacts |
|
| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
|
| Date Materialised |
|
|
|
|
Sectors submitted by the Researcher |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
| Project URL: |
|
| Further Information: |
|
| Organisation Website: |
http://www.strath.ac.uk |