| EPSRC Reference: |
GR/L70066/01 |
| Title: |
A NEW CHIRAL AUXILIARY FOR ORGANIC SYNTHESIS |
| Principal Investigator: |
Afarinkia, Dr K |
| Other Investigators: |
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| Department: |
Chemistry |
| Organisation: |
Kings College London |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 October 1998 |
Ends: |
30 September 2001 |
Value (£): |
53,842
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| EPSRC Research Topic Classifications: |
| Chemical Synthetic Methodology |
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| EPSRC Industrial Sector Classifications: |
| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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We have recently discovered an unprecedented diatereoselective reaction of enolates derived from asymmetric alpha-ketophosphonate with electrophiles. We now plan to extend our investigation and prepare a number of enantiomerically pure alpha-ketophosphonate and measure the diasteroininduction in the reaction of their enolate with eletrophiles. To demonstrate the usefulness of this methodology, we intend to apply it to the synthesis of a wide range of enantiomerically pure compounds. The methodology will be highlighted by the synthesis of (+) -intergerrinicic acid.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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