| EPSRC Reference: |
GR/L53687/01 |
| Title: |
ALKENYLOXAZOLINES AND RELATED COMPOUNDS AS AZA-DIENES IN ASYMMETRIC DIELS-ALDER CYCLOADDITIONS |
| Principal Investigator: |
Elliott, Dr MC |
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| Department: |
Chemistry |
| Organisation: |
Cardiff University |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 October 1997 |
Ends: |
31 March 2001 |
Value (£): |
48,289
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Summary on Grant Application Form |
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The asymmetric hetero-Diels-Alder reactions of 2-alkenyloxazolines will be investigated. This class of hetero-diene is particularly attractive in view of their ready availability from inexpensive alpha-aminoacids. This methodology will provide a rapid entry into the synthesis of highly functionalised piperidines. These compounds are interesting in their own right, and also as building blocks for the synthesis of larger chiral molecules of biological interest. Diels-Alder reaction of 2-alkenyloxazolines with hetero-dienophiles such as isocyanates promises a general approach to non-natural alpha- and beta-aminoacids.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.cf.ac.uk |