EPSRC Reference: |
GR/L23642/01 |
Title: |
SOLVENT & PRESSURE CONTROL OF ORGANIC CRYSTALLIZATION APPLICATION TO PHARMACEUTICALS |
Principal Investigator: |
Shekunov, Dr B |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
Unknown (Data Transfer) |
Organisation: |
De Montfort University |
Scheme: |
Standard Research (Pre-FEC) |
Starts: |
01 October 1996 |
Ends: |
31 December 1996 |
Value (£): |
68,033
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EPSRC Research Topic Classifications: |
Biological & Medicinal Chem. |
Design of Process systems |
Materials Synthesis & Growth |
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EPSRC Industrial Sector Classifications: |
Pharmaceuticals and Biotechnology |
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Related Grants: |
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Panel History: |
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Summary on Grant Application Form |
The main aim of this project is to develop new clean methodology for crystallization of expansive organic materials, particularly, inhalation pharmaceuticals. This purpose will be achieved by using two prinicple techniques: recrystallization from supercritical fluids (SCF) and high-pressure crystallization. Novel in situ analytical methods, based on ultra-fast interferometry, will be developedto study the phase diagrams, particle formation and fluid hydodynamics. This programme will enable us to create a fundamental apporach to such phenomena and to apply this methodology to a variety of drugs. This work will be performed in a close industrial collaboration with Astra Charnwood (Loughborough).
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Key Findings |
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Potential use in non-academic contexts |
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Impacts |
Description |
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Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
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Project URL: |
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Further Information: |
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Organisation Website: |
http://www.dmu.ac.uk |