| EPSRC Reference: |
GR/L13476/01 |
| Title: |
THE DESIGN OF EFFICIENT RECYCLABLE CATALYSTS FOR ELECTROPHILIC AROMATIC SUBSTITUTION REACTIONS |
| Principal Investigator: |
Barrett, Professor T |
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| Department: |
Chemistry |
| Organisation: |
Imperial College London |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 November 1996 |
Ends: |
31 March 2000 |
Value (£): |
159,440
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| EPSRC Research Topic Classifications: |
| Catalysis & Applied Catalysis |
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| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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The conversation of simple aromatic molecules. such as benzene, toluene, etc. into more heavily funcitonalised, higher value molecules represent transformations of considerable economic significance. This proposal concerns the design of novel lanthanide catalysts (MX3) for electrophilic aromatic substitution reactions with expoxides or aldehydes to provide (2-hydroxyalkyl) - and (1-hydroxyalkyl) - benzene derivatives respectively. The catalysts will be designed to be water tolerant and thereby recyclable. It is the goal of this programme to prepare arylalkanols using heterogeneous catalysts (immobilised MX3) in reactions that liberate no acidic or inorganic waste streams. The lanthanide salts will be rendered insoluble by ion exchange with Nafion resin and by completion with in the macrocyclic cavity of a polymer supported phthalocyanine derivative. The chemistry in this proposal is directly relevant to several major fragrance chemicals including 1- and 2-phenylethanols and 4, 5, 5, 6, 7, 7-hexamethyl=1H-indano [2, 3-c] pyran (Galaxolide). The catalysts developed during the course of this research should be of general use in organic, pharmaceutical and fine chemical synthesis.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.imperial.ac.uk |