| EPSRC Reference: |
GR/K98353/01 |
| Title: |
USE OF ANALYTICAL HPLC SYSTEM IN COMBINATORIAL CHEMISTRY |
| Principal Investigator: |
Balasubramanian, Professor S |
| Other Investigators: |
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| Department: |
Chemistry |
| Organisation: |
University of Cambridge |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 April 1996 |
Ends: |
31 March 1999 |
Value (£): |
29,125
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| EPSRC Research Topic Classifications: |
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| EPSRC Industrial Sector Classifications: |
| Pharmaceuticals and Biotechnology |
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Summary on Grant Application Form |
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We intend to develop the use of analytical HPLC for the routine analysis of organic reactions carried out on resins. Automated cleavage of resin-bound samples, using the autosampling system will be investigated. The HPLC photodiode-array detector ad 3-D spectral analysis capacity will be utilised to investigate the scope for analytically resolving the individual components of compound libraries (as mixtures). The highly sensitive fluorescence HPLC detector will be exploited to develop novel encoding strategies that employ fluorescent tag molecules.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.cam.ac.uk |