EPSRC Reference: |
GR/K89412/01 |
Title: |
ASYMMETRIC SYNTHESIS USING NON-ENZYMIC PROTEINS AND POLYPEPTIDES |
Principal Investigator: |
Roberts, Professor S |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
Chemistry |
Organisation: |
University of Liverpool |
Scheme: |
ROPA |
Starts: |
01 October 1996 |
Ends: |
30 September 1997 |
Value (£): |
41,118
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EPSRC Research Topic Classifications: |
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EPSRC Industrial Sector Classifications: |
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Related Grants: |
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Panel History: |
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Summary on Grant Application Form |
The oxidation of selected sulfides and selenides using potassium persulfate in the presence of various albumins or other proteins (eg globulins) will be explored. The employment of one sulfoxide for the preparation of tetrahydrolipstatin will be investigated. The optimum reaction conditions will be applied to the oxidation of a selection of ketones and electron rich alkenes. The employment of home-made polypeptides (eg, poly-(L)-leucine) under the same reaction conditions will also be investigated. The sterocontrolled oxidative rearrangement of selenides will be studied.
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Key Findings |
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Potential use in non-academic contexts |
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Impacts |
Description |
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Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
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Project URL: |
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Further Information: |
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Organisation Website: |
http://www.liv.ac.uk |