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Details of Grant 

EPSRC Reference: EP/Z532964/1
Title: EPSRC MediForge Hub: Industry 5.0 Medicines Manufacturing Research Hub
Principal Investigator: Florence, Professor AJ
Other Investigators:
Nordon, Professor A Sefcik, Professor J Love, Professor S
Galindo, Professor A Schroeder, Professor SLM Brown, Dr C
Smith, Dr R Litster, Professor JD Bourne, Professor RA
Johnston, Professor BF Jackson, Professor G Adjiman, Professor CS
Chapman, Professor P Markl, Dr D Cardona, Dr J
Researcher Co-Investigators:
Project Partners:
Applied Materials AstraZeneca Bruker
Cambridge Crystallographic Data Centre Chiesi Pharmaceuticals Clairet Scientific Ltd
CPI DigiM Eli Lilly and Company (International)
F. Hoffmann-La Roche (International) National Manufacturing Inst Scotland Pfizer
Sanofi (International) Siemens Healthineers Takeda Pharmaceuticals International Gmb
Technobis Crystallization Systems UCB ULab Equipment Ltd.
Department: Inst of Pharmacy and Biomedical Sci
Organisation: University of Strathclyde
Scheme: Standard Research TFS
Starts: 01 July 2024 Ends: 30 June 2031 Value (£): 11,895,078
EPSRC Research Topic Classifications:
Artificial Intelligence Carbon Capture & Storage
Design & Testing Technology Drug Formulation & Delivery
EPSRC Industrial Sector Classifications:
Manufacturing Pharmaceuticals and Biotechnology
Related Grants:
Panel History:  
Summary on Grant Application Form
We will also create a diverse, inclusive, and interdisciplinary MediForge Living Lab environment for co-creation of medicine manufacturing research, technology, open innovation and staff development (Platform 4). Core to the Hub is providing national leadership in the research, development and innovation community for Industry 5.0 medicines manufacturing to drive adoption of digital transformation CMC procedures in industry (Platform 5). The central focus of the Hub is to take the lead in the national research, development, and innovation community for Industry 5.0 medicine manufacturing, driving the digital transformation of CMC procedures for sustainable medicines manufacturing.

MediForge will facilitate the transformation of medicine development and production for affordable, sustainable healthcare; accelerate patient access to new medicines; ensure a resilient supply of quality medicines; address the climate crisis and enable the workforce of the future to thrive in a culture of open innovation and entrepreneurship for placed-based economic growth.uture workforce to realise the goals of Industry 5.0. The Hub aims to: transform our system-wide understanding of molecules to the final product through the development of:

- a novel integrated cyber-physical research infrastructure

- a world-first medicine development and manufacturing data fabric

- a reconfigurable end-to-end manufacturing testbed

This will be delivered through five research platforms, focusing on creating a system of cyber-physical platforms that integrate scale-down processes with various technologies like AI, robotics, and smart sensors (Platform 1). We will create and connect a data fabric that links material properties, process settings and final product attributes, and advanced system-wide models to inform a real-time digital twin of the entire manufacturing process (Platform 2). The real-time digital twin will drive a new flexible and resilient system for manufacturing pharmaceuticals using modular and reconfigurable technology to increase efficiency and adaptability.

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Organisation Website: http://www.strath.ac.uk