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Details of Grant 

EPSRC Reference: EP/Y009347/1
Title: Establishing an overseas collaboration to explore the use of digital holographic microscopy to study the biomechanics of fibrous substrates
Principal Investigator: Ortega Asencio, Dr I
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Clinical Dentistry
Organisation: University of Sheffield
Scheme: Overseas Travel Grants (OTGS)
Starts: 01 May 2024 Ends: 30 April 2025 Value (£): 22,560
EPSRC Research Topic Classifications:
Biophysics Chemical Biology
EPSRC Industrial Sector Classifications:
Healthcare
Related Grants:
Panel History:  
Summary on Grant Application Form
Developing new biomaterials that closely reproduce the complexity of the human body and therefore ensure high functionality remains a big scientific challenge. Many biomaterial design approaches have been followed to reproduce chemically and topographically the extracellular matrix (ECM); however, the biomechanics of these biomaterials is sometimes poorly understood as the characterisation of cell-substrate interactions can be an onerous task. The work Dr. Ortega proposes here aims to secure funding to visit a laboratory in Spain to explore the use of new techniques to understand substrate biomechanics in a more approachable, reproducible and reliable way. Specifically, Dr. Ortega plans to explore the use of digital holographic microscopy (DHM) for characterising fibrous substrate biomechanics. The proposal involves the PI visiting a recognised European Centre (Universidad Miguel Hernandez de Elche, UMH) to develop an international collaboration with this university and work together in a project grant proposal for Horizon Europe. Dr. Ortega will visit Prof. Antonio Fimia Gil which is a world-recognised expert in Optics specifically in DHM.

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Organisation Website: http://www.shef.ac.uk