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Details of Grant 

EPSRC Reference: EP/X025470/1
Title: the future use of injectable medicines outside the hospital: Increasing capacity in the NHTransforming S
Principal Investigator: Watts, Dr AG
Other Investigators:
Wilson, Professor P Martinez Hernandez, Dr U Fotaki, Professor N
Simsek, Professor Ö Fincham Haines, Dr TS
Researcher Co-Investigators:
Project Partners:
Corsham Science Limited
Department: Pharmacy and Pharmacology
Organisation: University of Bath
Scheme: Standard Research
Starts: 01 January 2024 Ends: 31 December 2028 Value (£): 3,358,334
EPSRC Research Topic Classifications:
Design & Testing Technology Drug Formulation & Delivery
Environment & Health Manufact. Business Strategy
EPSRC Industrial Sector Classifications:
Manufacturing Healthcare
Pharmaceuticals and Biotechnology
Related Grants:
Panel History:
Panel DatePanel NameOutcome
15 Nov 2022 Prosperity Partnership Round 5 Full Proposal Announced
Summary on Grant Application Form
Aseptic compounding is an area where practice has been transformed by the emergence of more complex, personalised medicines. The demands on aseptic dispensing are continually increasing, with clinical teams relying on increasingly complex compounds for treatments given every single day.

This Prosperity Partnership aims to create a platform that will transform the future use of injectable medicines in the UK and globally. We envisage, ultimately, a range of reformulated injectable medicines suited to the setting in which they are administered, whether in the community or a hospital, manufactured through an automated process dramatically reducing the demand placed on healthcare resource required to deliver them in whatever setting is appropriate. This potentially requires a wholesale reconfiguration of compounding service in England around a hub and spoke model with high degrees of standardisation and the adaption/adoption of new approaches to automation making more efficient use of resources both in pharmacy/compounding and in the nursing workforce transforming the use of injectable medicines. Underpinning the interlinked delivery of these medicines is a continual drive for extended shelf-lives (stability), simplicity in administration, volume of manufacture, supply chain and cost reduction.

Our project focusses on the nexus of these points, considering medicine formulation, manufacture and distribution as a whole system, where elements of the compounding process can occur across different sites, with different scalability and optimisation depending on both use/requirement and shelf-life/complexity of formulation and aseptic manufacturing facility requirements. This incorporates implementing robotics manufacturing and AI into the heavily regulated area of high variation medicines production.

Key Findings
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Potential use in non-academic contexts
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Impacts
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Summary
Date Materialised
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Project URL:  
Further Information:  
Organisation Website: http://www.bath.ac.uk