EPSRC logo

Details of Grant 

EPSRC Reference: EP/N026322/1
Title: Personalised nanomedicine for cancer therapy
Principal Investigator: Battaglia, Professor G
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Chemistry
Organisation: UCL
Scheme: EPSRC Fellowship
Starts: 01 September 2016 Ends: 31 August 2021 Value (£): 1,488,629
EPSRC Research Topic Classifications:
Drug Formulation & Delivery Materials Characterisation
Materials Synthesis & Growth
EPSRC Industrial Sector Classifications:
Healthcare Pharmaceuticals and Biotechnology
Related Grants:
Panel History:
Panel DatePanel NameOutcome
19 Apr 2016 EPSRC Physical Sciences Fellowship Interview 19 and 20 April 2016 Announced
18 Feb 2016 EPSRC Physical Sciences Materials - February 2016 Announced
Summary on Grant Application Form
After decades of research, cancer is still one of the top killers responsible for almost 15% of the total death worldwide per year. One of the most critical limitation for cancer therapy is our inability to direct anticancer drugs to cancerous cells maximising killing and minimising side effects (often worse than the disease itself). This is due to the fact that cancer cells are the same healthy cells gone wrong and hence share many similarities with the good cells complicating detection and targeting. I propose here the engineering of ultra-small carriers (as small as a virus and 100 times smaller than cancer cells) that will be equipped with unique chemical signature to target almost exclusively cancer cells. These nanocarriers will also be able to carry a lot of drugs and deliver them right inside the cells where the drug is most effective. Once their job is done, the material that makes the carrier is dissolved into the same nutrients used by our body. Most importantly we will design nanocarriers using patient-derived tissues so to create a fully personalised targeting profile as well as a personalised drug dosage.
Key Findings
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Potential use in non-academic contexts
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Impacts
Description This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Summary
Date Materialised
Sectors submitted by the Researcher
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Project URL:  
Further Information:  
Organisation Website: