| EPSRC Reference: |
EP/M506837/1 |
| Title: |
3D Stem Cell Printing for Animal-Free Drug Development |
| Principal Investigator: |
Shu, Professor W |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Sch of Engineering and Physical Science |
| Organisation: |
Heriot-Watt University |
| Scheme: |
Technology Programme |
| Starts: |
01 September 2014 |
Ends: |
29 February 2016 |
Value (£): |
124,951
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| EPSRC Research Topic Classifications: |
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| EPSRC Industrial Sector Classifications: |
| Healthcare |
Pharmaceuticals and Biotechnology |
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| Related Grants: |
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| Panel History: |
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Summary on Grant Application Form |
Printing tissues and mini-organs have recently been achieved by using modified ink-jet printer technology enabling the field
of biofabrication. The novel method of direct printing live cells opens up new paradigm in tissue science and engineering for
drug discovery and therapeutic applications. We have pioneered the world first valve based bioprinter that is capable of
printing human embryonic stem cells without damaging the cells while maintaining their biological functions. This project
aims to develop the first commercial stem cell bioprinter baed on the valve-based printing technology, working in a
consortium led by the global player in robotic control (Renishaw Ltd) and a SME (ClydeBiosciences Ltd) specialised in
developing human heart muscle cells from stem cells for drug testing. We will develop a new type of stem cell printer by
integrating IP protected 3d printing platform from Renishaw with existing valve based cell printing technology. The new
platform will then be validated for producing human heart and liver tissues using human stem cells from leading stem cell
company Roslin Cellab Ltd) and testing their responses to drugs. The new tool will not only allow us to produce high quality
human tissue for potentially more reliable animal free drug testing, but also enable a range of high throughput applications
for pharmaceutical industry, biotechnology companies and stem cell biologists.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.hw.ac.uk |