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Details of Grant 

EPSRC Reference: EP/I037237/1
Title: Cell Control in a Petri Dish (CCPD) Collaborative Network
Principal Investigator: Chan, Professor W
Other Investigators:
Rose, Professor FRA
Researcher Co-Investigators:
Project Partners:
Department: Sch of Pharmacy
Organisation: University of Nottingham
Scheme: Standard Research
Starts: 01 May 2011 Ends: 30 April 2013 Value (£): 125,919
EPSRC Research Topic Classifications:
Biological & Medicinal Chem.
EPSRC Industrial Sector Classifications:
Related Grants:
Panel History:
Panel DatePanel NameOutcome
21 Feb 2011 ChemBio Collaborative Networks Announced
Summary on Grant Application Form
The human body is made up of tissues and organs that are themselves made up of smaller components known as cells. Changes in these cell populations influence how they function and can result in the tissue becoming diseased or affecting how well it repairs and regenerates. We can isolate these cells from the body, grow them in a Petri dish in the laboratory and use them to study disease and the regenerative process. In addition, we can use them to screen new drugs to see how they are effective they are and confirm that they do not damage other tissues (such as the liver). Over the years, chemists have been designing and making small molecules primarily as new drugs to treat diseased cells but recent research has suggested that we can use these molecules in the laboratory to make normal cells diseased or to influence cell populations involved in the repair process known as stem cells. By doing this, we will be able to understand the cell in much greater detail and this knowledge will undoubtedly lead to better treatments in the future. To do this though, we need cell biologists and chemists, who are often based in separate departments and buildings and may not even know each other, to work more closely together. The aim of this network is to bring these scientists together, along with people based in industry, and create an environment for discussion and to encourage them to embark on this new research area to better understand how small molecules can influence cell function.
Key Findings
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Potential use in non-academic contexts
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Impacts
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Summary
Date Materialised
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Project URL: http://www.nottingham.ac.uk/pharmacy/cell-control-in-a-petri-dish.aspx
Further Information:  
Organisation Website: http://www.nottingham.ac.uk