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Details of Grant 

EPSRC Reference: EP/I031561/1
Title: Creativity@home-Novel Tools for Single Cell Manipulation
Principal Investigator: Ces, Professor O
Other Investigators:
Neil, Professor MAA Endres, Dr RG Klug, Professor DR
Templer, Professor R
Researcher Co-Investigators:
Project Partners:
Department: Dept of Chemistry
Organisation: Imperial College London
Scheme: Standard Research
Starts: 26 August 2011 Ends: 25 August 2012 Value (£): 101,750
EPSRC Research Topic Classifications:
Complex fluids & soft solids Lasers & Optics
Tools for the biosciences
EPSRC Industrial Sector Classifications:
Healthcare
Related Grants:
Panel History:  
Summary on Grant Application Form
Cells which are amongst the smallest units of life are made up of smaller components including lipids and proteins that combine together to perform functions that are vital to the life of the cell. Lipids form the backbone of membranes that help to compartmentalize them whereas proteins are the worker molecules in cells, making, building and moving things throughout. Interestingly, these molecules do not work in isolation, instead they often come together to perform higher order functions and their levels throughout a cell vary both as a function of time and space. They fluctuate as a function of time in response to stimuli, some external and some internal to the cell. Unfortunately, the state of the art in terms of our ability to measure the inner workings of these systems is such that it is still not possible to measure the protein levels in or accurately deliver or remove material to or from a single cell (either to the surface of to a sub-cellular location). This proposal puts forwards a series of feasibility studies to trial a series of new technologies that have the ability to address these technological bottlenecks thereby unlocking the inner workings of cells.
Key Findings
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Summary
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Further Information:  
Organisation Website: http://www.imperial.ac.uk