Details of Grant 

EPSRC Reference:	EP/H009604/1
Title:	Predicting the acclimatisation of microbial wastewater treatment communities as a function of the environment, random immigration, birth and death
Principal Investigator:	Sloan, Professor WT
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department:	Civil Engineering
Organisation:	University of Glasgow
Scheme:	Standard Research
Starts:	30 June 2010	Ends:	28 February 2014	Value (£):	208,277
EPSRC Research Topic Classifications:	Water Engineering
EPSRC Industrial Sector Classifications:	Environment Water
Related Grants:	EP/H012133/1
Panel History:	Panel Date Panel Name Outcome 26 Nov 2009 Process Environment and Sustainability Panel Announced
Summary on Grant Application Form
For a wastewater treatment plant to work dozens, perhaps hundreds, of different species of bacteria and protozoa must come together to form a microbial community that will transform the waste into biomass, CO2 or some other, hopefully less harmful, substance. Once formed the microbial community will often go through processes of acclimatisation where it adapts to changes in environmental conditions. This is a fundamental aspect of all biological treatment that, at present we can only engineer empirically. There is no a priori method for determining how long it will take for a reactor to acquire or lose a particular adaptation and practitioners are often have little more to go on than luck and judgment. In this proposal we aim to develop mathematical model for predicting acclimitisation. We will conduct a definitive set of experiments along with a comprehensive statistical analysis to ascertain the relative importance of environmental and stochastic effects in determining the composition of microbial communities used to treat wastewater. We will concentrate on the predicting shifts in community composition that will occur in response to systematic changes in ambient temperature. This has particular relevance to anaerobic systems which are attractive to the water industry because of their low carbon foot print, but are very sensitive to low temperatures. Cold adapted methanogenic communities are known to exist and in principle they could be used to seed a cold adapted anaerobic reactor. However, if such a reactor was run at ambient temperatures it would lose its cold adaptation in warmer months. Thus a theoretical framework for predicting the rate of acclimatisation in a reactor could be used very widely. Applications could stretch far beyond the environmental services industry. The same conceptual and mathematical approach will have value in all open microbiological systems be they engineered, medical or agricultural and could be critical to the application of engineered organisms envisaged in the nascent field of synthetic biology.
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Organisation Website:	http://www.gla.ac.uk