Details of Grant 

EPSRC Reference:	EP/F068352/1
Title:	New Multi-Component Reactions For Array Synthesis
Principal Investigator:	Stockman, Professor RA
Other Investigators:
Researcher Co-Investigators:
Project Partners:	GlaxoSmithKline plc (GSK)
Department:	Sch of Chemistry
Organisation:	University of Nottingham
Scheme:	Standard Research
Starts:	01 June 2008	Ends:	31 May 2011	Value (£):	305,871
EPSRC Research Topic Classifications:	Chemical Synthetic Methodology Combinatorial Chemistry
EPSRC Industrial Sector Classifications:	Pharmaceuticals and Biotechnology
Related Grants:
Panel History:	Panel Date Panel Name Outcome 27 Mar 2008 Array Chemistry (2nd Call) Announced
Summary on Grant Application Form
The project will develop new methods for so-called Multi-Component Reactions which will be able to generate arrays of amines and sulfonamides with a stereogenic (handed) centre next to the nitrogen functionality with complete control over each and every group attached to the nitrogen and the adjacent stereogenic carbon. The method will bring together up to six components in one reaction vessel to give single products in a predictable and controlled manner. By varying the six components any one of a huge number of potential chiral amines can be accessed, therefore allowing medicinal chemists easy access to either large numbers of chiral amines or specific sub-sets of chiral amines with ease and accuracy.
Key Findings
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Potential use in non-academic contexts
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Impacts
Description This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk Summary Date Materialised
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Project URL:
Further Information:
Organisation Website:	http://www.nottingham.ac.uk