| EPSRC Reference: |
EP/D064295/1 |
| Title: |
Induced Atropisomerism / Applications in Asymmetric Organocatalysis |
| Principal Investigator: |
Lygo, Professor B |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Sch of Chemistry |
| Organisation: |
University of Nottingham |
| Scheme: |
Standard Research |
| Starts: |
01 October 2006 |
Ends: |
28 February 2010 |
Value (£): |
342,037
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| EPSRC Research Topic Classifications: |
| Asymmetric Chemistry |
Chemical Synthetic Methodology |
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| EPSRC Industrial Sector Classifications: |
| Chemicals |
Pharmaceuticals and Biotechnology |
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| Related Grants: |
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| Panel History: |
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Summary on Grant Application Form |
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One of the great challenges in synthetic chemistry is to develop small-molecule catalysts that can exert high levels of control the stereochemical course of bond-forming processes. In this project we propose to undertake an ambitious programme of study designed to probe whether conformationally dynamic biphenyls can be combined with simple chiral amines to generate a diverse array of organic catalysts for asymmetric synthesis. As part of this study we plan to investigate application of these catalysts in a range of important carbon-carbon and carbon-oxygen bond forming processes. This project will involve a combination of traditional organic synthesis, computational chemistry and robotic synthesis/screening, and we believe that our established expertise in these areas will ensure a high degree of success.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.nottingham.ac.uk |