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Details of Grant 

EPSRC Reference: EP/D03194X/1
Title: Raman Spectroscopy of Prebiotic Chemicals of Relevance to Astrobiology (COST D27 Working Group WG06)
Principal Investigator: Edwards, Professor HG
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Faculty of Life Sciences
Organisation: University of Bradford
Scheme: Standard Research (Pre-FEC)
Starts: 30 September 2005 Ends: 29 September 2008 Value (£): 20,838
EPSRC Research Topic Classifications:
Chemical Structure
EPSRC Industrial Sector Classifications:
No relevance to Underpinning Sectors
Related Grants:
Panel History:  
Summary on Grant Application Form
This project forms part of a European research Working Group in pre-biotic chemistry and early evolution. All living organisms are composed of cells and the formation of the first cells (protocells) was a critical step in the origin of life processess. Lipid vesicles are now considered to be reasonable models of these early protocells; the chemical interactions between the simple lipid biomembranes, ions and uncharged molecules are key factors for the stabilisation and growth of the lipid matrices. Of special importance is the influence of water on the hydrophilic and hydrophobic regions of the lipid vesicles which affects the permeabilty of the prototype membranes towards other biomolecules such as proteins and amino acids. Raman spectroscopy is a micro-analytical technique for evaluating molecular interactions and consequent changes in biomolecules. Raman spectroscopy is now being evaluated for inclusion as novel instrumentation on planetary landers for the detection of extinct or extant extraterrestrial life. A Raman database of biomolecular signatures and their interaction with geological matrices will be extended in this project to include the lipid membrane-water-support systems to be studied here. These data will eventually inform future space mission probes as well as current studies of terrestrial extremophiles which exist at the limits of life in stressed enviromental conditions.
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Organisation Website: http://www.brad.ac.uk