| EPSRC Reference: |
EP/C522842/1 |
| Title: |
Chiral imidazolium salt hybrids for organo- and metal mediated-catalysis |
| Principal Investigator: |
Douthwaite, Dr R |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Chemistry |
| Organisation: |
University of York |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
18 July 2005 |
Ends: |
17 October 2008 |
Value (£): |
208,642
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| EPSRC Research Topic Classifications: |
| Asymmetric Chemistry |
Chemical Synthetic Methodology |
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| EPSRC Industrial Sector Classifications: |
| Chemicals |
Pharmaceuticals and Biotechnology |
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| Panel History: |
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Summary on Grant Application Form |
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The discovery and development of catalysts has revolutionised our ability to produce molecules, from bulk to fine chemicals, for a myriad of uses in modern society. Asymmetric catalysis represents one of the most challenging areas of organometallic and organic chemistry for the production of chiral molecules, and there is a clear need to develop new catalysts capable of improving known reactions or catalysing new transformations.The proposed research aims to prepare, apply and develop a new class of chiral compound for direct application to asymmetric catalytic bond formation and as precursors to chiral ligands for metal-mediated asymmetric catalysis. Specifically hybrid chiral imidazolium salts will be investigated as organocatalysts for C-C bond formation using multiple hydrogen bonding between a carbonyl oxygen atom and a hybrid imidazolium catalyst. In addition new imidazolium salts will be used as N-heterocyclic carbene ligand precursors for metal mediated synthesis of chiral amines via hydroamination of alkenes.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.york.ac.uk |