| EPSRC Reference: |
EP/C510135/1 |
| Title: |
Novel Fluorescence Lifetime Imaging Technology for Life Sciences Application |
| Principal Investigator: |
Suhling, Professor K |
| Other Investigators: |
|
| Researcher Co-Investigators: |
|
| Project Partners: |
|
| Department: |
Physics |
| Organisation: |
Kings College London |
| Scheme: |
First Grant Scheme Pre-FEC |
| Starts: |
01 October 2005 |
Ends: |
30 September 2008 |
Value (£): |
124,152
|
| EPSRC Research Topic Classifications: |
| Cells |
Development (Biosciences) |
| Light-Matter Interactions |
Optical Devices & Subsystems |
|
| EPSRC Industrial Sector Classifications: |
|
| Related Grants: |
|
| Panel History: |
|
|
Summary on Grant Application Form |
|
Minimally invasive and non-destructive imaging methods for the life sciences is a source of great excitement for medical imaging, cell biology and high throughput screening communities. Fluorescence lifetime imaging (FLIM) exploits recent advances in ultrafast laser and detector technology to realise imaging of live biological and other systems. By reporting not only the localisation but also the local environment of fluorophores, it provides new opportunities to study intracellular and intercellular processes, to non-invasively contrast different types and states of tissue and to enhance high throughput screening technologies.' propose to develop new instrumentation for FLIM, which I have invented and patented. The method I propose ,., based on wide-field photon counting imaging with an electron-bombarded CCD (EBCCD) and has and has key advantages over existing FLIM technology.This research at the boundary of physics, chemistry and biology highlights the way much of scientific research will be carried out in the future - with implications of how we should train scientist today.
|
|
Key Findings |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Potential use in non-academic contexts |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Impacts |
|
| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
|
| Date Materialised |
|
|
|
|
Sectors submitted by the Researcher |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
| Project URL: |
|
| Further Information: |
|
| Organisation Website: |
|