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Details of Grant 

EPSRC Reference: EP/Z534778/1
Title: Autonomous Scanning Probe Microscopy for Life Sciences and Medicine powered by Artificial Intelligence
Principal Investigator: Pyne, Dr ALB
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Chemical & Biological Engineering
Organisation: University of Sheffield
Scheme: Other JeS Guarantee Calls TFS
Starts: 01 November 2024 Ends: 31 October 2028 Value (£): 267,923
EPSRC Research Topic Classifications:
EPSRC Industrial Sector Classifications:
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Panel History:  
Summary on Grant Application Form
Artificial Intelligence is pushing forward the Industrial Revolution 4.0, which is transforming many areas of Society, including Science

and Technology. Nanoscopy, a recognized pillar of the research and manufacture of Nanotechnology-based products, is among the

areas that more quickly is adopting Artificial Intelligence. Machine learning algorithms are being developed and integrated in

microscopes for its autonomous operation and in software toolboxes for the automatic analysis of large volumes of microscopy data.

Scanning Probe Microscopy is particularly active in this integration with a special focus in the Life Sciences and Medical fields.

Scanning probe microscopes powered by machine learning are expected to enable the autonomous and label-free nanoscale

structural and functional (mechanical and electric) imaging of living cells and functional biomolecules in their native conditions,

something never achieved in nanoscopic imaging. The objective of the SPM4.0 Doctoral Network is to train a new generation of

researchers in the science and technology of autonomous Scanning Probe Microscopes powered by Artificial Intelligence for

applications in the Life Science and Medical fields. The researchers of the network will acquire a state-of-the-art multidisciplinary

scientific training in advanced scanning probe microscopy and machine learning and in their biological and medical applications. In

addition, they will receive training on complementary and transferable skills to increase their employability perspectives and to

qualify them to access to responsibility job positions in the private and public sectors. The final aim is to promote the wide adoption

of SPM4.0 technologies in public and private research centers and in industrial and metrology institutions and to explore new

horizons in the Life Sciences and Medical sectors regarding label-free nanoscopic cell imaging, illness diagnosis, or drug nanocarrier

development, consolidating Europe as world leader.
Key Findings
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Potential use in non-academic contexts
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Impacts
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Summary
Date Materialised
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Further Information:  
Organisation Website: http://www.shef.ac.uk