| EPSRC Reference: |
EP/Z534651/1 |
| Title: |
Advancing the development and implementation of hologenomics in biological sciences |
| Principal Investigator: |
Hall, Professor L J |
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| Department: |
Institute of Microbiology and Infection |
| Organisation: |
University of Birmingham |
| Scheme: |
Other JeS Guarantee Calls TFS |
| Starts: |
01 September 2024 |
Ends: |
31 August 2028 |
Value (£): |
267,923
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Summary on Grant Application Form |
Basic biology as well as applied fields such as agrobiology, biomedicine or biotechnology are undergoing a revolution driven by the realisation that microorganisms impact virtually all biological processes. Microorganisms associated with complex organisms are no longer considered passive passengers but active crews that continuously interact with their host to shape a wide range of biological
functions that play a key role in major basic and applied processes. The application of the newest high throughput molecular technologies to address such interplay has given rise to the novel field of hologenomics, which entails the joint analysis of host
genomes and microbial metagenomes with the aim of understanding the impact of host-microbiota interactions in basic and applied biological processes. The DN HoloGen has been conceived to lead the development and practical implementation of hologenomics in order to gain a more comprehensive understanding of host-microbiota interactions, and their impact in both basic and applied areas with direct relevance to many of the global societal challenges. We propose to form an unprecedented multidisciplinary and scientifically sound training network by bringing together top researchers with theoretical knowledge on symbiosis biology, microbial ecology, animal evolution, animal production and biomedicine, as well as practical expertise in large- scale (meta)genomics, DNA sequence analysis, metabolomics, computational biology and biological systems modelling. We anticipate that the research results will be (i) of academic relevance through development of new analytical frameworks and understandings of host-microbiome interactions, (ii) of direct relevance to the portfolios of the industrial partners, and (iii) through these portfolios stand to benefit the European Research and Innovation community.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.bham.ac.uk |