EPSRC logo

Details of Grant 

EPSRC Reference: EP/Y035186/1
Title: EPSRC Centre for Doctoral Training in Chemical Biology: Empowering UK BioTech Innovation
Principal Investigator: Barter, Dr LMC
Other Investigators:
Woscholski, Dr R Brooks, Dr NJ Tate, Professor EW
Vilar Compte, Professor R Ces, Professor O
Researcher Co-Investigators:
Project Partners:
ADC Therapeutics (UK) Limited Advanced Research Clusters Management Lt Agilent Technologies Ltd
AstraZeneca BactoBio Ltd BASF
Cancer Research UK Convergence Science Centre for Process Innovation CPI (UK) Clustermarket Ltd
CodeBase Ltd Create Education Ltd Dayhoff Labs
Diamond Light Source FreshCheck FungiAlert
GlaxoSmithKline plc (GSK) Hammersmith and Fulham Council IBM UK Ltd
Institute of Cancer Research Lewtas Science and Technologies MedCity
Micrographia BIO Mitsui Fudosan (U.K.) Ltd National Physical Laboratory NPL
NIHR Imperial Biomedical Research Centre Novartis Nutropy
Octopus Ventures Procter & Gamble R&M Healthtech Limited
Revena Limited Royal Botanic Gardens Kew Scale Space
SOSV Limited SynbiCITE SynBioVen Limited
Syngenta Synthace Limited Technical University of Munich
The Francis Crick Institute The University of Hong Kong Ubiquigent Ltd
Undaunted Upstream Vertex Pharmaceuticals
WOOST Ltd Yoo Capital Limited
Department: Chemistry
Organisation: Imperial College London
Scheme: Centre for Doctoral Training
Starts: 01 October 2024 Ends: 31 March 2033 Value (£): 7,617,935
EPSRC Research Topic Classifications:
Biological & Medicinal Chem. Chemical Biology
EPSRC Industrial Sector Classifications:
Pharmaceuticals and Biotechnology
Related Grants:
Panel History:
Panel DatePanel NameOutcome
20 Nov 2023 EPSRC Centres for Doctoral Training Interview Panel G November 2023 Announced
Summary on Grant Application Form
Chemical biology is spearheading the development & translation of novel molecular tools and technologies to study biology and develop biomedical understanding. Dovetailing these platforms with industry 4.0/5.0 breakthroughs in automation & robotics, artificial intelligence & machine learning, the CDT will unlock the Lab of the Future paradigm. This will redefine the state of the art with respect to making, measuring, modelling & manipulating molecular interactions in biological systems, leading to novel R&D workflows, promoting efficient design-test cycles and driving sustainability.

These molecular technologies will (i) enable biological & medical research, (ii) revolutionise understanding of disease & (iii) create novel diagnostics, drugs & therapies, focusing increasingly on individual patient outcomes. They will also impact the agri-tech sector which faces huge demand to increase productivity by unlocking strategies to e.g. track agrochemicals in plants/soil, understand modes of action & drive precision farming. Similarly, advances in personal care industrial processes are critically dependent on development of molecular technologies to gain insight into structured product design.

The application of novel molecular tools/technologies, Lab of the Future strategies & their commercialisation through the instrumentation science sector is thus critical to the UK economy, supporting >4,500 healthcare, personal care, agri-science & biotech companies. This will transform (i) therapeutic, agrochemical & personal care product discovery (ii) med-tech/biotech/healthcare instrumentation R&D pipelines & (iii) stimulate creation of SMEs. Working closely with civic partners including Hammersmith & Fulham Council and the NHS, the CDT's talent & research pipeline will act as a growth engine for one of the most rapidly expanding Life Science ecosystems in Europe, the White City Innovation District.

Given the importance of Chemical Biology to UK plc there is great demand but short supply of Chemical Biology PhD graduates able to match the pace of innovation across the physical/life science interface, at a time when industry & health sectors need these skills to accelerate productivity. The CDT in Chemical Biology: Empowering UK BioTech innovation with its unique 5 year programme: 1 year MRes + 3 year PhD + 1 year ELEVATE Fellowship directly addresses this skills gap by training a new generation of career-ready graduates, able to embrace the Lab of the Future concept and unlock its potential by fusing innovative molecular tools & tech with industry 4.0 & 5.0 advances to study molecular interactions & develop applications in the life science, agriscience & personal care sectors.

CDT students will benefit from a research and training programme created with >100 industry/external stakeholders designed to meet future employer's needs. Our cohort-based programme with EDI at its heart, will allow students to contextualise their work within wider CDT activities & find novel solutions to their research, supported by one of the world's largest Chemical Biology communities: the Institute of Chemical Biology (>165) research groups.

Students will be trained in multidisciplinary blue skies/translational research, lean innovation, scale fast/fail fast approaches, creating scientists able to understand molecular technologies, sustainable product design, early-stage commercialisation, & industry's pace of change. To support this, our training includes Future Lab & HackEDU courses (prototyping training), a drug screening programme, Biz-Catalyst (entrepreneurial training), InnovaLab (SME accelerator), a Data Science course, Human Centred Design, Science Communication (with BBC) & Bioethics/RRI/Sustainability/Policy courses. Following PhD completion, students can enter the ELEVATE fellowship programme, bridging the gap between PhD & industry/academia, offering training, personalised workplace opportunities & enable students to kickstart new companies.
Key Findings
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Potential use in non-academic contexts
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Impacts
Description This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Summary
Date Materialised
Sectors submitted by the Researcher
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Project URL:  
Further Information:  
Organisation Website: http://www.imperial.ac.uk