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Details of Grant 

EPSRC Reference: EP/N019393/1
Title: Catalyst Diversity from Chiral Palladacycles
Principal Investigator: Richards, Dr C
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Chemistry
Organisation: University of East Anglia
Scheme: Standard Research
Starts: 01 June 2016 Ends: 31 May 2019 Value (£): 323,525
EPSRC Research Topic Classifications:
Catalysis & Applied Catalysis Co-ordination Chemistry
EPSRC Industrial Sector Classifications:
No relevance to Underpinning Sectors
Related Grants:
Panel History:
Panel DatePanel NameOutcome
03 Dec 2015 EPSRC Physical Sciences Chemistry - December 2015 Announced
Summary on Grant Application Form
Catalytic methodologies have a very major impact on improving the efficiency and cost effectiveness of synthesis, a key (usually the key) technology for the development of new medicines, agrochemicals, materials, fragrances and, in turn, further catalysts. This programme will generate a platform for the discovery of chiral palladium catalysts for use in asymmetric synthesis based upon a new method of catalyst formation. This will allow numerous catalysts to be generated in just one step from palladium-based complexes, the synthesis of which has been pioneered within the Richards group. Access to a diverse array of palladium catalysts will enable the optimisation of selectivity and the minimisation of the quantity of catalyst required in a host of reactions. In addition, the new catalyst generation protocol will enable facile immobilisation, boosting further the sustainability of the chemistry through catalyst recovery and reuse. The new platform will be applied to the selective synthesis of novel and varied chiral (i.e. handed) structures, diversity generation lying at the heart of the process of discovering new bioactive compounds for application in drug discovery programmes.
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