EPSRC Reference: |
EP/I010173/1 |
Title: |
Beating Hearts at High Resolution: Adaptive High Resolution Selective Plane Illumination Microscopy |
Principal Investigator: |
Love, Professor G |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
Physics |
Organisation: |
Durham, University of |
Scheme: |
Standard Research |
Starts: |
01 March 2011 |
Ends: |
31 March 2015 |
Value (£): |
506,510
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EPSRC Research Topic Classifications: |
Development (Biosciences) |
Lasers & Optics |
Optical Phenomena |
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EPSRC Industrial Sector Classifications: |
Pharmaceuticals and Biotechnology |
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Related Grants: |
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Panel History: |
Panel Date | Panel Name | Outcome |
08 Jul 2010
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Physical Sciences - Physics
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Announced
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Summary on Grant Application Form |
In this project we will film life as it develops in the heart by exploiting developments in optical microscopy, high speed imaging, and adaptive optics. The hearts will be in live, developing zebrafish and mouse embryos. This is extremely challenging as the living heart is large (on a microscopic scale), is embedded in the body of the animal (meaning it must be imaged at depth) and is beating, and therefore moving, at a rate of around 300 beats per minute. As well as providing a challenge to demonstrate the advanced methods we will develop the study of cardiac development is important both for investigating the development of the healthy heart and for determining the causes of heart problems.
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Key Findings |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Project URL: |
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Further Information: |
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Organisation Website: |
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