| EPSRC Reference: |
EP/G013160/1 |
| Title: |
Quantifying the Interplay of Structure and Reactivity in Ring Closing and Cross Metathesis |
| Principal Investigator: |
Percy, Professor JM |
| Other Investigators: |
|
| Researcher Co-Investigators: |
|
| Project Partners: |
|
| Department: |
Pure and Applied Chemistry |
| Organisation: |
University of Strathclyde |
| Scheme: |
Standard Research |
| Starts: |
21 July 2009 |
Ends: |
20 July 2012 |
Value (£): |
256,115
|
| EPSRC Research Topic Classifications: |
| Chemical Synthetic Methodology |
Physical Organic Chemistry |
|
| EPSRC Industrial Sector Classifications: |
|
| Related Grants: |
|
| Panel History: |
| Panel Date | Panel Name | Outcome |
|
25 Sep 2008
|
Physical Organic Chemistry Panel 2
|
Announced
|
|
|
Summary on Grant Application Form |
|
The proposed programme will use a number of synthetically accessible systems to improve our quantitative understanding of the organic reaction mechanism of the alkene ring closing methathesis (RCM) and cross metathesis (CM) reactions. We wish to determine effective molarities (EMs) as a function of ring size n and substitution patterns, to measure absolute cyclisation and oligomerisation rates, and to use computational methods to understand these data. The programme will develop expertise and tools in physical organic chemistry (experimental kinetics, computational methods) while investigating a reaction of considerable fundamental importance and acute current relevance. We propose to use computational and experimental kinetic techniques synergistically to refine and/or challenge fundamental and general ideas about aspects of the mechanism of RCM reactions, bringing the reaction within the domain of expertise of POC. We also wish to develop complementary insight concerning cross metathesis (CM) reactions, insights which are required if we are to understand the issues surrounding cyclisation efficiency fully. The successful delivery of this programme will advance research knowledge significantly and make a considerable contribution to UK standing in the important and topical field of alkene metathesis chemistry.
|
|
Key Findings |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Potential use in non-academic contexts |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Impacts |
|
| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
|
| Date Materialised |
|
|
|
|
Sectors submitted by the Researcher |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
| Project URL: |
|
| Further Information: |
|
| Organisation Website: |
http://www.strath.ac.uk |