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Details of Grant 

EPSRC Reference: EP/F009410/1
Title: Directed Reconfigurable Nanomachines
Principal Investigator: Cronin, Professor L
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: School of Chemistry
Organisation: University of Glasgow
Scheme: Standard Research
Starts: 01 November 2007 Ends: 31 October 2010 Value (£): 205,294
EPSRC Research Topic Classifications:
Chemical Synthetic Methodology Surfaces & Interfaces
EPSRC Industrial Sector Classifications:
No relevance to Underpinning Sectors
Related Grants:
EP/F00981X/1 EP/F009852/1 EP/F010109/1
Panel History:  
Summary on Grant Application Form
We propose a scheme to revolutionise the synthesis of nanodevices, nanomachines, and, ultimately, functional materials via the positional assembly of molecules and nanoscale building blocks. Computer-directed actuators will be used to drive (with sub-nanometre to sub-Angstrom precision) the elements of a nanosystem along pre-defined and entirely deterministic trajectories, thereby achieving structures not accessible by mimicking natural assembly strategies alone. Linkages and bonding between the building blocks will also be initiated, modulated, and - in some cases - terminated by direct computer control. Our proposal rests on the parallel development of novel surface-bound, reconfigurable nanoscale building blocks (molecules, functionalised clusters, nanoparticles) and advanced techniques for automated assembly of matter. We focus on the generation of two major and immensely challenging functionalities for positionally-assembled nanomachines: switchable energy transduction and conformationally-driven motion. Our archetypal system comprises the following units: an energy harvester, a switchable/gateable link, and an optical or mechanical output. By arranging, configuring, and triggering these fundamental units our long-term goal is no less than the fabrication of an autonomous, abiotic nanomachine.
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Organisation Website: http://www.gla.ac.uk