| EPSRC Reference: |
EP/E021042/1 |
| Title: |
Colloidal Cell Delivery Systems |
| Principal Investigator: |
Alexander, Professor C |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Sch of Pharmacy |
| Organisation: |
University of Nottingham |
| Scheme: |
Standard Research |
| Starts: |
15 January 2007 |
Ends: |
14 January 2010 |
Value (£): |
186,268
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| EPSRC Research Topic Classifications: |
| Complex fluids & soft solids |
Drug Formulation & Delivery |
| Materials Synthesis & Growth |
Surfaces & Interfaces |
| Tissue Engineering |
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| EPSRC Industrial Sector Classifications: |
| Healthcare |
Pharmaceuticals and Biotechnology |
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| Related Grants: |
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| Panel History: |
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Summary on Grant Application Form |
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As stem cell technologies advance towards clinical application there is an urgent need to enhance the methods of delivering these cells into the body. Current methods of simple injection of cell suspensions are crude because they waste cells, compromise viability and generate poor starting conditions for the regeneration of a tissue. In this collaborative project between the universities of Nottingham and Manchester we will establish an injectable material consisting of a colloid mixture of cells and particles that is injectable at room temperature and aggregates into a porous colloidal gel at body temperature. This material could form the basis for cell delivery in neurology, endocrinology, hepatology, orthopaedics and many other areas because the components are well understood and trusted materials with long track records of use in the body. A successful outcome for this project will prove the principle of cell delivery into skeletal muscle tissue using temperature-triggered assembly and establish the fundamental principles involved.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.nottingham.ac.uk |