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EPSRC Support by Research Area (Chemical Biology and Biological Chemistry) in Theme (Physical Sciences)

Research areas are used to describe EPSRC's portfolio of excellent long term research and high quality postgraduate training.

Grants are classified using one or more research areas. The number and value of grants listed below reflects how the theme portfolio is described by this research area.

Please note: some research areas will appear under multiple themes. There is no unique, absolute, relationship between a research area and a theme.

Grant TitlePrincipal
OrganisationDepartmentTotal Grant
Value (£)
A Chemical Toolkit to Define Formaldehyde’s Enigmatic BiologyHopkinson, Dr RJUniversity of LeicesterChemistry 397,133
A nitrenoid strategy to access sp3-rich nitrogen heterocyclesDavies, Dr PWUniversity of BirminghamSchool of Chemistry 444,751
A Platform for Chemical Probe Identification and Optimization Facilitating Interrogation of Biological MechanismsWilson, Professor AJUniversity of LeedsSch of Chemistry 1,147,345
A Protein Functionalization Platform Based on Selective Modification at Methionine ResiduesGaunt, Professor MUniversity of CambridgeChemistry 1,892,760
A regionally strategic NMR spectrometer with globally unique high pressure and reaction monitoring capabilityAdams, Dr RWUniversity of Manchester, TheChemistry 1,698,226
A Research Dedicated Mini-Cyclotron for PET Ligand DiscoveryGouverneur, Professor VUniversity of OxfordOxford Chemistry 771,540
A solid-state NMR instrument for Northern IrelandManesiotis, Dr PQueen's University of BelfastSch of Chemistry and Chemical Eng 956,055
Aberration-Corrected Scanning Transmission Electron Microscope with atomic resolution spectroscopy under controlled environmental conditions: AC-eSTEMLazarov, Professor VUniversity of YorkPhysics 3,250,534
An Artificial RibosomeTurberfield, Professor AJUniversity of OxfordOxford Physics 664,201
An Artificial RibosomeO'Reilly, Professor RKUniversity of BirminghamSchool of Chemistry 581,943
An EPSRC National Research Facility to facilitate Data Science in the Physical Sciences: The Physical Sciences Data science Service (PSDS)Coles, Professor SJUniversity of SouthamptonSch of Chemistry 2,996,067
Anti tumour agents from natural products - new approaches to targeting ultra potent analogues of the duocarmycinsSearcey, Professor MUniversity of East AngliaPharmacy 450,207
Boron: Beyond the ReagentLloyd-Jones, Professor GUniversity of EdinburghSch of Chemistry 5,012,847
Chemical biology tools for investigating the chemistry of cellular REDOX stressConway, Professor SJUniversity of OxfordOxford Chemistry 5,334,387
Chemical Tools for Probing Histone Deacetylase Multiprotein Complexes in DiseaseHodgkinson, Dr JTUniversity of LeicesterChemistry 246,269
Controlling cell-free expression with temperature-sensitive polymer-DNA conjugatesBooth, Dr MJUCLChemistry 188,645
C-Terminal Selective Ligation to Access Homogeneous Antibody ConjugatesBaker, Professor JRUCLChemistry 444,295
Directed Molecular Recognition through Next-Generation Hybrid Molecular ImprintingTurner, Professor NWDe Montfort UniversitySchool of Pharmacy 270,150
Directed Molecular Recognition through Next-Generation Hybrid Molecular ImprintingFulton, Dr DANewcastle UniversitySch of Natural & Environmental Sciences 308,037
Dynamic physicochemical nanoscale imaging at the solid-liquid interfaceGeorge, Professor MUniversity of NottinghamSch of Chemistry 1,171,682
Electron Microscopy of Selected Proteins and Protein Complexes Through Preparative Mass SpectrometryRauschenbach, Professor SUniversity of OxfordOxford Chemistry 367,126
EPSRC-SFI: Glycoconjugate tools for sensing endoglycosidase activity: a diagnostic sugar probe for heparanaseMiller, Professor GJKeele UniversityFaculty of Natural Sciences 368,582
Expanding the chemical range of RNA-mediated catalysis : structure and mechanismLilley, Professor DMJUniversity of DundeeSchool of Life Sciences 551,849
Exploiting Membrane Lipidation for Advanced Drug DeliverySanderson, Dr JMDurham, University ofChemistry 201,184
High throughput 2D-IR analysis of biomolecules under physiological conditionsHunt, Professor NTUniversity of YorkChemistry 1,006,129
Hyperfine Resolution and Advanced Structural Analysis to Enable Next-Generation Molecular ScienceO'Connor, Professor PBUniversity of WarwickChemistry 3,101,722
Interrogating the Nisin:lipid II Interaction: A Chemical Biology ApproachCochrane, Dr SQueen's University of BelfastSch of Chemistry and Chemical Eng 243,690
Interrogating the nisin:lipid II interaction: a chemical biology approachTabor, Professor AUCLChemistry 759,213
Ion Beam Analysis for the 2020's and Beyond: An Integration of Elemental Mapping and 'omics'Bailey, Professor MJUniversity of SurreyChemistry 1,025,483
Irreversible Molecular Glues to Activate Anti-Cancer Interactome of 14-3-3sigmaDoveston, Dr RGUniversity of LeicesterChemistry 410,167
Mapping membrane protein dynamics in time and space with mass spectrometryPolitis, Dr AUniversity of Manchester, TheSchool of Biological Sciences 1,018,512
Meta-Smart: Merging de novo designed biomolecules with plasmonic metamaterials for new technologiesKadodwala, Professor MUniversity of GlasgowSchool of Chemistry 1,022,161
Modify-catch-release-repeat: Reversible bioconjugations for controlled release of small molecules from antibodies and their fragmentsFascione, Dr M AUniversity of YorkChemistry 397,840
Mussel-inspired tough and stiff injectable gels from inter-linked microgelsSaunders, Professor BUniversity of Manchester, TheMaterials 292,934
NAMS: Native ambient mass spectrometryCooper, Professor HJUniversity of BirminghamSch of Biosciences 1,241,472
Nanostar Sieving for Oligonucleotides Manufacture (NanoSieveOligo)Livingston, Professor AQueen Mary University of LondonSchool of Engineering & Materials Scienc 486,259
New Directions in Bioisostere ResearchAnderson, Professor EAUniversity of OxfordOxford Chemistry 572,768
Next generation molecular imaging and therapy with radionuclidesBlower, Professor PKings College LondonImaging & Biomedical Engineering 6,437,106
Next-generation mass spectrometry of protein structure and interactionsBenesch, Professor JUniversity of OxfordOxford Chemistry 601,538
North East Ultrafast Transient Absorption Spectroscopy FacilityGibson, Professor EANewcastle UniversitySch of Natural & Environmental Sciences 902,433
PEPR - A centre for Pulse Electron Paramagnetic Resonance spectroscopy at Imperial CollegeRoessler, Dr MMImperial College LondonChemistry 2,288,049
Properties and applications of Janus faced fluorocyclohexanesO'Hagan, Professor DUniversity of St AndrewsChemistry 482,983
Property-Enhanced PorphyrinsChauvet, Dr A A PUniversity of SheffieldChemistry 379,306
Self-Assembled Cryptate Kinase Inhibitors as Anti-Cancer Therapeutic Agents.Rice, Professor CUniversity of HuddersfieldChemistry 481,054
Shining Light on Metalloprotein Mechanism: Single Protein Crystal Catalytic Studies Driven by 'Caged' Electron SourcesAsh, Dr PAUniversity of LeicesterChemistry 186,373
Simulating catalysis: Multiscale embedding of machine learning potentialsvan der Kamp, Dr MWUniversity of BristolBiochemistry 391,585
Site-selective functionalisation of peptides and proteins via free-radical-induced dechalcogenationMitchell, Dr NJUniversity of NottinghamSch of Chemistry 428,349
Smart hydrophilic/ hydrophobic switches for targeted membrane deliveryHaynes, Dr C J EUCLChemistry 391,336
Software for experimentally driven macromolecular modellingDegiacomi, Dr MDurham, University ofChemistry 687,453
Spins and superconducting circuits for advanced spectroscopy (SpinSUPER)Roessler, Dr MMImperial College LondonChemistry 1,063,137
Stopped-Flow NMR Spectroscopy for the Physical and Life SciencesPulis, Dr A PUniversity of LeicesterChemistry 808,397
Structure, mechanism and assembly of a nano-scale biological rotary electric motorBerry, Professor RMUniversity of OxfordOxford Physics 2,042,298
Synthesis of novel brevicidine and laterocidine analogues active against multi-drug-resistant Gram-negative bacteriaCochrane, Dr SQueen's University of BelfastSch of Chemistry and Chemical Eng 391,380
The UK Dynamic Nuclear Polarisation Magic Angle Spinning NMR FacilityKockenberger, Dr WUniversity of NottinghamSch of Physics & Astronomy 1,857,395
The UK Dynamic Nuclear Polarisation Magic Angle Spinning NMR FacilityLee, Dr DUniversity of Manchester, TheChem Eng and Analytical Science 2,881,145
The UK Dynamic Nuclear Polarisation Magic Angle Spinning NMR FacilityGrey, Professor CPUniversity of CambridgeChemistry 247,949
The UK High-Field Solid-State NMR National Research FacilityWilliamson, Dr PTFUniversity of SouthamptonSch of Biological Sciences 51,797
The UK High-Field Solid-State NMR National Research FacilityBlanc, Professor FUniversity of LiverpoolChemistry 23,982
The UK High-Field Solid-State NMR National Research FacilityBrown, Professor SPUniversity of WarwickPhysics 2,431,378
The UK High-Field Solid-State NMR National Research FacilityAshbrook, Professor SEMUniversity of St AndrewsChemistry 30,069
The UK High-Field Solid-State NMR National Research FacilityTitman, Dr JUniversity of NottinghamSch of Chemistry 43,315
The UK High-Field Solid-State NMR National Research FacilityGriffin, Dr JLancaster UniversityChemistry 22,420
VIRTACs - Protein Degradation as an Anti-Viral StrategyFrance, Dr D JUniversity of GlasgowSchool of Chemistry 402,635

Total Number of Grants: 63
Total Value of Grants: £67,249,028

The grant value may include the cost of access to facilities (these funds are not awarded to the grant holding organisation).