| EPSRC Reference: |
EP/Y003519/1 |
| Title: |
Every Ion Counts: 4-D Mass Spectrometry |
| Principal Investigator: |
Smith, Dr B |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Electrical Engineering and Electronics |
| Organisation: |
University of Liverpool |
| Scheme: |
Standard Research - NR1 |
| Starts: |
01 January 2024 |
Ends: |
31 December 2025 |
Value (£): |
165,827
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| EPSRC Research Topic Classifications: |
| Analytical Science |
Chemical Biology |
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| EPSRC Industrial Sector Classifications: |
| No relevance to Underpinning Sectors |
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| Related Grants: |
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| Panel History: |
| Panel Date | Panel Name | Outcome |
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24 May 2023
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ECR International Collaboration Grants Panel 3
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Announced
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Summary on Grant Application Form |
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Recent innovations have elevated mass spectrometry (MS) into a ubiquitous and indispensable analytical technique. However, the increasing complexity of the instrument has gradually turned it into a closed system whereby specific methods are suitable for only a narrow range of well-defined applications/analyses. We propose a new and radical approach to how we perform ion spectrometric analyses - new modes of operation for such experiments. The key enabler of this concept relies on two novel modes for MS analysis in which contrasting polarities are accessible in addition to the traditional positive and negative modes - what we have termed "four dimensional (4D) MS". The 4D MS strategy has potential to generate up to 50% more analytical data, and to enable new experiments including isomer differentiation, enhanced mixture classification and high confidence molecular weight assignments on any ordinary standalone mass spectrometer. This project can lead to the formation of new MS capability providing a means for more comprehensive measurement by way of 4D-MS.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.liv.ac.uk |